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Yuhan inks export deal to develop treatment for liver disease

All News 09:25 January 07, 2019

By Kim Han-joo

SEOUL, Jan. 7 (Yonhap) --South Korean drugmaker Yuhan Corp. said Monday that it has signed a US$785 million deal with U.S. biotechnology firm Gilead Sciences Inc. to export its new liver disease treatment technology.

The deal calls for the two companies to enter into a collaboration agreement to co-develop novel therapeutic candidates for the treatment of patients with advanced fibrosis due to nonalcoholic steatohepatitis (NASH), officials said.

Yuhan will maintain commercialization rights to develop and commercialize novel small molecules, with Gilead to acquire global rights, officials said.

Both will jointly conduct pre-clinical research, while Gilead will be responsible for global clinical development, corporate sources said.

The deal includes upfront payment of $15 million, and Yuhan will receive another $770 million in potential milestone payments upon achievement of certain developments, officials said.

Yuhan will be entitled to further royalties depending on future net sales, Yuhan said without disclosing more.

NASH is a chronic and progressive liver disease characterized by fat accumulation of more than five percent and inflammation in the liver. The disease, which currently has limited treatment, can lead to fibrosis that affects liver function.

The logo of Yuhan Corp. (Yonhap)


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